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Image Search Results
Journal: Frontiers in Microbiology
Article Title: 1-((2,4-Dichlorophenethyl)Amino)-3-Phenoxypropan-2-ol Kills Pseudomonas aeruginosa through Extensive Membrane Damage
doi: 10.3389/fmicb.2018.00129
Figure Lengend Snippet: Genetic analysis of SPI009 mode of action. (A) Functional enrichment of the obtained set of sensitive (black bars) and resistant (white bars) mutants using PseudoCAP classifications. P -values were determined using a two-tailed Fisher’s exact test (α = 0.05). PseudoCAP counts represent the number of mutants in the respective classes. (B) Functional enrichment analysis of the up- and downregulated differentially expressed genes (log 2 fold change >1) as determined after RNA sequencing upon treatment with SPI009. A two-tailed Fisher’s exact test was used to determine P -values for the classes of downregulated genes (white bars), upregulated genes (black bars), and the total set (gray bars).
Article Snippet: Identified non-synonymous mutations were confirmed via PCR amplification and
Techniques: Functional Assay, Two Tailed Test, RNA Sequencing